改善 CAR-T 细胞治疗对病毒性疾病、癌症和自身免疫性疾病疗效的分子机制最新进展

Recent advances in molecular mechanisms to improve the efficacy of CAR-T cell therapy for viral diseases, cancer, and autoimmune diseases.

CRISPR 工程化 CAR-T 细胞治疗 EB 病毒相关鼻咽癌：新兴治疗前景综述

CRISPR-Engineered CAR-T Cell Therapy for Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma: A Review of Emerging Therapeutic Prospects.

CAR-T 细胞治疗中的精准重编程：先进基因编辑的创新、挑战与未来方向

Precision Reprogramming in CAR-T Cell Therapy: Innovations, Challenges, and Future Directions of Advanced Gene Editing.

下一代 CAR-NK 细胞治疗：工程化策略、转化挑战与肿瘤免疫治疗的未来展望

Next-generation CAR-NK cell therapy: engineering strategies, translational challenges, and future perspectives in cancer immunotherapy.

通用型 CAR-T 细胞治疗的最新进展

Recent advances in universal chimeric antigen receptor T cell therapy.

从实验台到临床：实体恶性肿瘤 CAR-T 细胞治疗的新兴范式

From Bench to Bedside: Emerging Paradigms in CAR-T Cell Therapy for Solid Malignancies.

实体瘤过继细胞治疗：当前临床格局、挑战与未来方向

Adoptive cell therapies in solid tumors: current clinical landscape, challenges, and future directions.

通过大规模 CRISPRi 筛选鉴定增强靶向 B7-H3 的 CAR-T 细胞治疗胶质母细胞瘤的遗传修饰因子

Identification of genetic modifiers enhancing B7-H3-targeting CAR T cell therapy against glioblastoma through large-scale CRISPRi screening.

我们的研究凸显了基于 CRISPR 的基因筛选在探究肿瘤-CAR-T 相互作用方面的能力，并鉴定出肿瘤细胞中可成药的潜在靶点，这些靶点赋予肿瘤细胞对 CAR-T 细胞杀伤的耐药性。

基因编辑技术用于实体瘤 CAR-T 细胞治疗的潜力

Harnessing the potential of gene editing technology for CAR-T cell therapy of solid tumors.

从球状体到类器官：实体瘤 CAR-T 细胞治疗研究的下一代模型

From spheroids to organoids: next-generation models for CAR-T cell therapy research in solid tumors.