CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
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登记显示招募中的试验排在最前,共 5 项。同一状态内中国中心优先;具体中心是否开放须核实。信息来自 ClinicalTrials.gov、CDE 与 ChiCTR 公开登记。能否入组、费用与可及性,以登记原文和主治医生判断为准。
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Therapeutic melanoma vaccines: Platforms, neoantigen strategies, and emerging combination immunotherapies.
Clinical translation of mRNA-based cancer vaccines for solid tumors.
Advances and challenges in immunotherapy for intrahepatic cholangiocarcinoma based on the tumour immune microenvironment.
通过整合机制、临床证据、分子亚型和转化局限性,本综述为 ICC 中生物标志物指导的精准免疫治疗提供了一个平衡的框架。对肝内胆管癌免疫治疗的临床证据和局限性进行了批判性评估,重点强调了对更广泛胆道癌试验的 ICC 特异性解读。将 ICC 肿瘤免疫微环境整合到涉及基质、髓系、淋巴系和代谢调节的功能性免疫轴中。分子亚型和免疫相关生物标志物为 ICC 中生物标志物指导的精准免疫治疗提供了框架。当前 ICC 免疫治疗试验仍受限于异质性设计、ICC
Store-operated calcium signaling modulators improve a dendritic cell-based vaccine against melanoma.
Superior in-vivo efficacy of integrated tumor neoantigen vaccination with adoptive neoantigen-reactive T-cell therapy in solid tumor.
新抗原疫苗联合 NRT 细胞及抗 PD1 治疗在实体瘤中展现出强大的抗肿瘤疗效,是一种安全有效的新型免疫治疗手段。
Dendritic Cell Dysfunction Underlies Immune Escape After Adoptive Cellular Therapy in Glioblastoma.
PROTAC-Engineered Protein/DNA Nanoantigen is a Potent Booster for Dendritic Cell Vaccines in Cancer Immunotherapy.
Case Report: Primed dendritic cell immunotherapy for multiple solid tumors.
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