TIL(肿瘤浸润淋巴细胞)与乳腺放疗:国际免疫肿瘤生物标志物工作组展望
Tumour-infiltrating lymphocytes and breast radiotherapy: perspectives from the International Immuno-Oncology Biomarker Working Group.
TIL(肿瘤浸润淋巴细胞)(TILs)是乳腺癌的预后和预测生物标志物。
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Tumour-infiltrating lymphocytes and breast radiotherapy: perspectives from the International Immuno-Oncology Biomarker Working Group.
TIL(肿瘤浸润淋巴细胞)(TILs)是乳腺癌的预后和预测生物标志物。
Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer.
我们的研究结果表明,VG161与RT联合的最佳方案是在VG161感染后6小时给予5 Gy照射,这能确保RT最大程度地促进VG161在BC中的复制。
Advances in TIL therapy: Expanding the horizons beyond melanoma.
TIL(肿瘤浸润淋巴细胞)疗法代表着实体瘤治疗的突破,满足了选择有限患者的未满足需求。
A prognostic and predictive computational pathology immune signature for ductal carcinoma in situ: retrospective results from a cohort within the UK/A
高 TIL 密度与更高的复发风险相关——尤其是浸润性复发——并且与 DCIS 患者更大的放疗获益相关。我们基于 TIL 的计算病理学特征在 DCIS 中具有预后和预测作用。
Tumor-infiltrating lymphocyte therapy in triple-negative breast cancer: from mechanistic exploration to clinical translation.
乳腺癌是女性常见的恶性肿瘤,其中三阴性乳腺癌(TNBC)是一种预后较差的亚型。
A T cell resilience model associated with response to immunotherapy in multiple tumor types.
这些结果证明了Tres在识别T细胞有效性生物标志物以及实体瘤免疫疗法潜在治疗靶点方面的实用性。
Breast Cancers Are Immunogenic: Immunologic Analyses and a Phase II Pilot Clinical Trial Using Mutation-Reactive Autologous Lymphocytes.
大多数乳腺癌患者产生了针对其癌症突变表达产物的天然免疫反应。TIL 过继转移是一种高度个性化的实验性选择,在此初步试验中显示能够介导 mBrCa 患者的客观缓解,值得进一步研究。
Phase Ib study of intratumoral talimogene laherparepvec (T-VEC) in combination with chemotherapy or endocrine therapy in patients with advanced HER2-n
在ABC且具有可注射局部区域病变的患者中,将瘤内注射T-VEC加入CT或ET是安全的,支持继续研究能够增强局部和全身免疫应答的直接瘤内免疫调节策略。
Changes in CD8-positive lymphocytes following chemotherapy with concomitant bevacizumab in HER2-negative breast cancer.
含贝伐珠单抗的化疗似乎可增强原发乳腺肿瘤中 CD8 阳性 TIL 的浸润,这可能有助于改善局部肿瘤消退和更好的治疗结局。
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