rhIL-7-hyFc(一种长效白细胞介素-7)提升 CAR-T 细胞治疗实体瘤的疗效
rhIL-7-hyFc, a long-acting interleukin-7, improves efficacy of CAR-T cell therapy in solid tumors.
本研究为 NT-I7 联合 CAR-T 细胞治疗人类实体瘤提供了依据。
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
RESULTS
rhIL-7-hyFc, a long-acting interleukin-7, improves efficacy of CAR-T cell therapy in solid tumors.
本研究为 NT-I7 联合 CAR-T 细胞治疗人类实体瘤提供了依据。
Therapeutic effiacy of T cells expressing chimeric antigen receptor derived from a mesothelin-specific scFv in orthotopic human pancreatic cancer anim
Engineering a juxtamembrane-targeting CAR T-cell against mesothelin: a novel binder resilient to shed antigen for enhanced efficacy against ovarian an
Neoleukin-2/15-armored CAR-NK cells sustain superior therapeutic efficacy in solid tumors via c-Myc/NRF1 activation.
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.
IL-12-armed oncolytic HSV-2 enhances CAR T cell efficacy against pancreatic cancer in xenografted models.
这种协同策略以降低的 CAR-T 剂量实现了持久而强效的肿瘤清除,为胰腺癌及其他具有挑战性的实体恶性肿瘤提供了一种变革性策略。
Efficacy of natural killer T and gammadelta T cells in mesothelin-targeted immunotherapy of pancreatic cancer.
Proton radiation boosts the efficacy of mesothelin-targeting chimeric antigen receptor T cell therapy in pancreatic cancer.
Advances, challenges, and innovative strategies of CAR-T cell therapy in pancreatic cancer.
One-step knock-in CAR constructs in human NK cells enable scalable, TGFβ1-resistant immunotherapy for solid tumors.
我们采用无病毒、一步工程化策略,设计了稳健的、抗 TGF 1 的同种异体 CAR-NK 细胞,建立了一种通用且临床可规模化的方法,用于工程化改造代谢增强的 CAR-NK 细胞,使其能够克服实体瘤中 TME 介导的免疫抑制。
全站检索
企业材料记录:CARVYKTI®(cilta-cel);CAR-T / In vivo CAR-T。具体来源核对范围见企业详情。
企业材料记录:BRL-101;基因编辑 / 细胞与基因治疗。具体来源核对范围见企业详情。
企业材料记录:vispa-cel / CB-011;CRISPR 编辑异体 CAR-T。具体来源核对范围见企业详情。
患者管理、毒性缓解、疗效评估;IMWG免疫治疗委员会
入排标准、采集、桥接、清淋、输注、疗效及并发症;成人B-ALL CAR-T临床实践核心中文文件
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