IL-12 通过重塑 CD8⁺ T 细胞动态并拓宽抗肿瘤免疫增强过继性细胞治疗

IL-12 augments adoptive cell therapy by reshaping CD8(+) T dynamics and broadening antitumor immunity.

CAR-T 疗法在实体瘤中的应用：当前机遇与挑战

Application of CAR-T therapy in solid tumors: current opportunities and challenges.

靶向 γ-分泌酶复合物调控高侵袭性恶性肿瘤中的致癌 NOTCH 信号：一项系统综述

Modulation of Oncogenic NOTCH Signaling in Highly Aggressive Malignancies by Targeting the γ-Secretase Complex: A Systematic Review.

针对 Dickkopf-1-A2 复合物工程化的 T 细胞可用于治疗 HLA-A2(+) 实体瘤和血液系统肿瘤

T cells engineered against Dickkopf-1-A2 complex can be used to treat HLA-A2(+) solid and hematologic cancers.

淋巴毒素 β 受体在实体瘤免疫及治疗靶向中的多效性与多细胞作用

Pleiotropic and multicellular roles of lymphotoxin beta receptor in solid tumor immunity and therapeutic targeting.

血小板工程化 CAR-T 细胞作为肿瘤术后辅助治疗

Platelet-engineered CAR-T cells as adjuvant therapy after cancer surgery.

肿瘤相关 Tn 和 STn 抗原：从分子机制到精准诊断与治疗

Tumor-associated Tn and STn antigens: from molecular mechanism to precision diagnosis and treatment.

Tn/STn 抗原在肿瘤发生和免疫逃逸中发挥关键作用，在诊断和治疗方面具有巨大潜力。未来研究应集中于阐明其潜在机制、开发创新检测技术，并促进多学科合作，以推动基于 Tn/STn 抗原的肿瘤分子分型、精准靶向治疗和疗效预测系统的发展，从而为癌症诊断和治疗提供新方向。

肽引导的适配器 CAR-T 细胞疗法治疗表达 SSTR2 的神经内分泌肿瘤

Peptide-guided adaptor-CAR T-Cell therapy for the treatment of SSTR2-expressing neuroendocrine tumors.

非信号胞外间隔区调控 CAR-T 细胞的肿瘤抗原选择性

Nonsignaling extracellular spacer regulates tumor antigen selectivity of CAR T cells.

新型靶向 CEACAM 的 2A3 单域抗体 CAR-T 细胞在体外和体内产生抗肿瘤作用

New CEACAM-targeting 2A3 single-domain antibody-based chimeric antigen receptor T-cells produce anticancer effects in vitro and in vivo.