胰腺癌新兴嵌合抗原受体免疫细胞治疗:机制、临床进展与未来展望
Emerging Chimeric Antigen Receptor-Immune Cell Therapy for Pancreatic Cancer: Mechanisms, Clinical Advances, and Future Perspectives.
肿瘤细胞治疗研究
DISEASE HUB
FOR TREATMENT
现在就能报名的(招募中)排在最前,共 0 项。同一状态内中国中心优先。信息来自 ClinicalTrials.gov、CDE 与 ChiCTR 公开登记。能否入组、费用与可及性,以登记原文和主治医生判断为准。
FOR RESEARCH
Emerging Chimeric Antigen Receptor-Immune Cell Therapy for Pancreatic Cancer: Mechanisms, Clinical Advances, and Future Perspectives.
Tumor tough, therapy smarter: Rethinking CAR-T for pancreatic cancer.
Tandem Dual CAR-T Cells Targeting HER2 and Mesothelin Enhance anti-Tumor Effects in Pancreatic Cancer.
Aberrant expression of collagen type X in solid tumor stroma is associated with EMT, immunosuppressive and pro-metastatic pathways, bone marrow stroma
COL10A1 相关基因网络作为侵袭性肿瘤表型的调控因子和生物标志物可能具有重要价值,对治疗开发和临床结局具有重要意义。识别 COL10A1 及其相关基因高表达的肿瘤,可能揭示具有增强 EMT 能力和转移潜能的骨髓来源基质微环境的存在。我们的分析可能有助于对乳腺癌和胰腺癌患者进行更有效的风险评估和更精准的治疗。
Aberrant expression of collagen type X in solid tumor stroma is associated with EMT, immunosuppressive and pro-metastatic pathways, bone marrow stroma
COL10A1 相关基因网络可能作为侵袭性肿瘤表型的调控因子和生物标志物具有重要价值,对治疗开发和临床结局具有重要意义。识别高表达 COL10A1 及其相关基因的肿瘤可能揭示具有增强 EMT 能力和转移潜能的骨髓来源基质微环境的存在。我们的分析可能有助于对乳腺癌和胰腺癌患者进行更有效的风险评估和更精准的治疗。
Therapeutic Efficacy of IL7/CCL19-Expressing CAR-T Cells in Intractable Solid Tumor Models of Glioblastoma and Pancreatic Cancer.
Antibody-dependent cellular cytotoxicity-inducing antibodies enhance the natural killer cell anti-cancer response against patient-derived pancreatic c
这些结果支持使用类器官作为一种相关的个性化模型,在体外研究 NK 细胞的抗肿瘤反应,以及 ADCC 诱导抗体增强 NK 细胞效应功能的潜力。
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