CTLA4 和 LAG3 单核苷酸多态性对接受 BCMA CAR-T 细胞治疗的多发性骨髓瘤患者的临床影响
Clinical Impact of CTLA4 and LAG3 Single-Nucleotide Polymorphisms in Multiple Myeloma Patients Treated With BCMA CAR T-Cell Therapy.
肿瘤细胞治疗研究
DISEASE HUB
FOR TREATMENT
现在就能报名的(招募中)排在最前,共 5 项。同一状态内中国中心优先。信息来自 ClinicalTrials.gov、CDE 与 ChiCTR 公开登记。能否入组、费用与可及性,以登记原文和主治医生判断为准。
FOR RESEARCH
Clinical Impact of CTLA4 and LAG3 Single-Nucleotide Polymorphisms in Multiple Myeloma Patients Treated With BCMA CAR T-Cell Therapy.
Efficacy and safety of frail patients treated with ciltacabtagene autoleucel in the real world: A Center for International Blood and Marrow Transplant
Cilta-cel 在体弱 RRMM 中仍然有效,但衰弱与生存期缩短和毒性增加相关,支持制定个体化的 CAR-T 策略。
Managing Novel CAR T-Cell Toxicities in Multiple Myeloma.
CAR-T Cell Therapy: Engineering Remission in Refractory Myeloma.
Phase 1 Study of Anito-cel, a d-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma.
Anito-cel 治疗在重度经治的复发/难治性多发性骨髓瘤患者中导致了高缓解率。3 级或更高级别的细胞因子释放综合征和 ICANS 罕见。(由 Arcellx 和 Kite,一家吉利德公司资助;ClinicalTrials.gov 注册号:NCT04155749。)
The Current Landscape and Prospects of iPSCs in BCMA-targeted Therapy for Multiple Myeloma.
In vivo CAR T-cell therapy: determinants of response and durability.
Persistence of mucosal CAR-T cells and inflammatory remodeling in enterocolitis associated with BCMA CAR-T cell therapy.
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