妇科肿瘤免疫治疗:当前证据、生物标志物驱动实践及未来方向
Immunotherapy in Gynecologic Cancers: Current Evidence, Biomarker-Driven Practice, and Future Directions.
肿瘤细胞治疗研究
DISEASE HUB
FOR TREATMENT
现在就能报名的(招募中)排在最前,共 1 项。同一状态内中国中心优先。信息来自 ClinicalTrials.gov、CDE 与 ChiCTR 公开登记。能否入组、费用与可及性,以登记原文和主治医生判断为准。
FOR RESEARCH
Immunotherapy in Gynecologic Cancers: Current Evidence, Biomarker-Driven Practice, and Future Directions.
WNK4 restrains endometrial cancer progression by reprogramming macrophage polarization toward an M1-like phenotype.
WNK4 在子宫内膜癌中作为免疫相关抑制因子,部分通过限制 M2 样极化和削弱巨噬细胞驱动的肿瘤支持发挥作用。
Exploring the Possible Role of Endometriosis-Associated Dysbiosis in Endometrial Carcinogenesis.
Natural killer cells at the interface of tumor immune escape and immunotherapy resistance in endometrial cancer.
The association of mismatch repair deficiency with histopathological parameters in endometrial carcinoma: A study from the kurdistan region of Iraq.
MMRd 以 MLH1/PMS2 缺失模式为主,与子宫内膜样组织学类型、肿瘤分级和 TIL(肿瘤浸润淋巴细胞)显著相关。MMRd 可作为有用的分子生物标志物和免疫微环境的潜在预测因子,支持其在预后和个体化治疗中的作用。
Immune heterogeneity and therapeutic resistance in gynecological malignancies.
Immunotherapy for gynecological tumors: From mechanism to clinical practice.
Multi-omics analysis positions DNA2 at the interface of genome integrity programs and tumor behavior in pan-cancer.
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