人源化与电荷优化的 CSPG4 特异性 CAR-T 细胞对头颈部鳞状细胞癌显示增强疗效
Humanized and Charge-Optimized CSPG4-Specific CAR-T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma.
开发用于头颈部鳞状细胞癌(HNSCC)的 CAR-T 细胞疗法面临的主要挑战包括:确定稳健的肿瘤抗原和合适的 CAR 设计。
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Humanized and Charge-Optimized CSPG4-Specific CAR-T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma.
开发用于头颈部鳞状细胞癌(HNSCC)的 CAR-T 细胞疗法面临的主要挑战包括:确定稳健的肿瘤抗原和合适的 CAR 设计。
Magnesium-Enhanced Magnetic Hyperthermia for Triggering Vaccine-Like Antitumor Immunotherapy.
我们的研究凸显了这种金属基水凝胶作为通用平台、通过协同免疫治疗策略增强抗肿瘤疗效的潜力。
Cancer stem cell mechanisms and targeted therapeutic strategies in head and neck squamous cell carcinoma.
头颈部鳞状细胞癌(HNSCC)起源于口腔、咽和喉的上皮衬里,2020 年全球新诊断病例超过 830,000 例,是第七大常见癌症。
CAR-T cell therapy and reconstructive oncologic surgery in peripheral solid tumors-A narrative review.
本综述探讨了将 CAR-T 细胞疗法与重建性肿瘤外科手术整合,用于治疗外周实体瘤,包括黑色素瘤、肉瘤、乳腺癌和头颈部癌。
Advances and challenges in CAR-T cell therapy for head and neck squamous cell carcinoma.
头颈部鳞状细胞癌(HNSCC)仍是最具侵袭性的恶性肿瘤之一,治疗选择有限,尤其是在复发和转移性病例中。
Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study.
这些数据表明,在晚期HNSCC中瘤内注射T4免疫疗法是安全的。
Claudin18.2 is a novel molecular biomarker for tumor-targeted immunotherapy.
The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective.
本研究提供了对选择性且精准靶向癌症所需联合靶点的身份和数量的计算估计。
Immunotherapy in locally advanced head and neck squamous cell carcinoma: The current status and future outlook.
头颈部鳞状细胞癌构成了重大的全球健康负担,大多数病例在局部晚期阶段被诊断,需要多模式治疗。
AI-mediated immunotherapeutics in adenoid cystic carcinoma: Challenges and current perspectives.
腺样囊性癌(AdCC)是一种少见、侵袭性强且无法治愈的头颈部肿瘤。
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