FRONTIER PAPERS
Exploiting RIG-I-like receptor pathway for cancer immunotherapy.
RIG-I 样受体(RLRs)是细胞内模式识别受体,可识别病毒或细菌感染并诱导宿主先天免疫反应。
CAR T-cell Efficacy in Solid Tumors Is Enhanced by Oncolytic Viruses.
溶瘤病毒在黑色素瘤和胶质瘤的小鼠模型中促进 CAR T 细胞疗效。
Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice.
编码多种转基因的溶瘤病毒(OVs)已被评估作为治疗工具,以提高嵌合抗原受体(CAR)修饰的T细胞在实体瘤微环境(TME)中的疗效。
Bispecific immunotherapy based on antibodies, T-cell receptors, and aptamers: mechanisms of action, adverse effects, and future perspectives.
在过去十年中,双特异性免疫治疗平台已从实验室原型进展到多中心临床试验,开启了精准肿瘤学的新轨迹。
An update on the clinical trial research of immunotherapy for glioblastoma.
采用当前标准治疗,中位总生存期不足 2 年。
New hopes for the breast cancer treatment: perspectives on the oncolytic virus therapy.
溶瘤病毒(OV)疗法已成为癌症治疗中一个有前景的前沿方向,尤其是针对实体瘤。
A Review of Current and Pipeline Drugs for Treatment of Melanoma.
恶性黑色素瘤是最具侵袭性的皮肤癌。
Biological Therapies in the Treatment of Cancer-Update and New Directions.
生物疗法通过靶向癌细胞同时减少对正常组织的影响,改变了肿瘤学的面貌。
Oncolytic human herpesvirus for cancer therapy.
单纯疱疹病毒(HSV)因其基因容量、对多种肿瘤的作用、触发免疫反应的能力以及对癌症微环境的适应性,在溶瘤治疗中具有吸引力。
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