人类乳腺癌中 T 细胞耗竭相关免疫环境的全面单细胞图谱
A comprehensive single-cell map of T cell exhaustion-associated immune environments in human breast cancer.
免疫检查点治疗在乳腺癌中仍局限于三阴性患者,且长期临床获益罕见。
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A comprehensive single-cell map of T cell exhaustion-associated immune environments in human breast cancer.
免疫检查点治疗在乳腺癌中仍局限于三阴性患者,且长期临床获益罕见。
Intratumoral delivery of dendritic cells plus anti-HER2 therapy triggers both robust systemic antitumor immunity and complete regression in HER2 mamma
HER2-DC1 i.t. 与抗 HER2 抗体联合通过协同激活 T 细胞和 B 细胞区室介导肿瘤消退,并提供证据表明 HER2-DC1 i.t.
Fusogenic vesicular stomatitis virus combined with natural killer T cell immunotherapy controls metastatic breast cancer.
将 NKT 细胞免疫疗法与增强型溶瘤病毒疗法相结合,增强了对肺转移的抗肿瘤免疫靶向作用,为转移性乳腺癌提供了一种有前景的治疗策略。
IL-17A functions and the therapeutic use of IL-17A and IL-17RA targeted antibodies for cancer treatment.
白细胞介素 17A(IL-17A)是 IL-17 细胞因子家族的主要成员,主要由辅助性 T 细胞 17(Th17)产生。
Short- and long-term efficacy of olaparib combined with chemotherapy in advanced triple-negative breast cancer.
奥拉帕利联合化疗增强了晚期 TNBC 的短期和长期疗效,改善了免疫功能,并延长了生存期,且未增加治疗相关毒性,支持其临床应用。
Immunological profiles of the breast cancer microenvironment represented by tumor-infiltrating lymphocytes and PD-L1 expression.
这些结果表明,hTILs 反映了肿瘤微环境中免疫应答的差异,并且某些免疫细胞组分在乳腺癌微环境的 PD-L1 通路中有利表达。
A pan-cancer multi-omics analysis of lactylation genes associated with tumor microenvironment and cancer development.
乳酸化基因参与恶性肿瘤形成。乳酸化评分可作为预测患者预后和免疫治疗疗效的有前景的生物标志物。
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