基于 DNA 超分子水凝胶的保护性 NK 细胞储库用于增强三阴性乳腺癌治疗
Protective NK Cell Reservoir Based on DNA Supramolecular Hydrogel for Enhanced Triple-Negative Breast Cancer Therapy.
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
非典型 B 细胞在乳腺癌中的预后价值
英文原题：Prognostic value of atypical B cells in breast cancer.
查看英文原题
Prognostic value of atypical B cells in breast cancer.
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中文摘要
肿瘤浸润性B细胞对乳腺癌（BRCA）预后的影响仍知之甚少。Yang等人最近的研究发现了一个非典型的、克隆扩增的活化Fc受体样4（FCRL4）+ B细胞群体，该群体与包括BRCA在内的多种肿瘤类型患者的总生存期改善相关。
展开英文摘要原文
The impact of tumor-infiltrating B cells on breast cancer (BRCA) outcomes remains poorly understood. Recent findings from Yang et al. identify an atypical, clonally expanded population of activated Fc receptor-like 4 (FCRL4) + B cells that is associated with improved overall survival in patients affected by various tumor types, including BRCA.
论文信息
- 作者
- García-Torralba E、Galluzzi L、Buqué A
- 第一作者单位
- Cancer Signaling and Microenvironment Program, Fox Chase Cancer Center, Philadelphia, PA, USA; Department of Medical Oncology, Hospital Universitario Morales Meseguer, Murcia, Spain; Department of Medicine, Medical School, University of Murcia, Murcia, Spain; IMIB-Arrixaca, Murcia, Spain.United States
- 通讯作者单位
- Cancer Signaling and Microenvironment Program, Fox Chase Cancer Center, Philadelphia, PA, USA. Electronic address: abuquemartinez@gmail.com.United States
- 文献类型
- 非美国政府资助研究
- 期刊
- Trends in cancer2024 Nov
- 原文标识
- PubMed 39353814 · DOI 10.1016/j.trecan.2024.09.009