CAR-T(CAR-T)细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CAR-T(CAR-T)细胞在血液系统恶性肿瘤中的应用推动了这种免疫治疗形式的显著进展。
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题:Q&A: Robert Vonderheide on Immunotherapy Advances.
Q&A: Robert Vonderheide on Immunotherapy Advances.
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研究人员和肿瘤学家长期以来一直将人体自身的防御机制视为攻克癌症的可能工具。为此,他们开发了检查点抑制剂、mRNA疫苗、CAR-T 细胞疗法及其他治疗方法。费城宾夕法尼亚大学Abramson癌症中心主任Robert Vonderheide(医学博士、哲学博士)谈论了该领域的发展历程以及未来前景。
Researchers and oncologists have long looked to the body's own defenses as a possible tool to conquer cancer. To that end, they have developed checkpoint inhibitors, mRNA vaccines, chimeric antigen receptor T-cell therapies, and other treatments. Robert Vonderheide, MD, DPhil, director of the Abramson Cancer Center at the University of Pennsylvania in Philadelphia, talks about where the field has been and what lies ahead.
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