基于 DNA 超分子水凝胶的保护性 NK 细胞储库用于增强三阴性乳腺癌治疗
Protective NK Cell Reservoir Based on DNA Supramolecular Hydrogel for Enhanced Triple-Negative Breast Cancer Therapy.
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
即将到来的治疗：伴中枢神经系统转移的乳腺癌患者
英文原题：Treatments on the Horizon: Breast Cancer Patients with Central Nervous System Metastases.
查看英文原题
Treatments on the Horizon: Breast Cancer Patients with Central Nervous System Metastases.
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中文摘要
综述目的：本文回顾文献中乳腺癌及中枢神经系统转移的新兴管理策略。随着肿瘤系统治疗不断发展，乳腺癌中枢神经系统转移的管理方法也在演进。 近期进展：本文介绍治疗策略如何从标准化疗发展为更具靶向性的方法、创新药物递送技术、免疫疗法和放疗，并综述乳腺癌及中枢神经系统转移领域即将出现的新疗法。未来治疗可能更有效地穿过血脑屏障，克服标准疗法的局限。这些开创性策略有望改善患者生活质量和生存期。
展开英文摘要原文
PURPOSE OF REVIEW: The goal of this paper is to provide a review on the current emerging management strategies as described in the literature pertaining to breast cancer and central nervous system metastases. As systemic oncology treatments evolve, so are new approaches to the management of central nervous system metastases from breast cancer.
RECENT FINDINGS: In this review, we describe how novel treatment strategies have evolved from standard chemotherapy to more targeted approaches, innovative drug delivery methodologies, immunotherapeutics, and radiotherapeutic approaches.
We describe innovative treatment strategies on the horizon for breast cancer and central nervous metastases. Future therapeutics may be better able to penetrate through the blood-brain-barrier bypassing limitations from standard therapies. These pioneering strategies will hopefully improve patients' quality of life as well as survival.
论文信息
- 作者
- Kaplan A、Li MJ、Malani R
- 第一作者单位
- Department of Neurology, Weill Cornell Medicine, New York, NY, USA.United States
- 通讯作者单位
- Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. malanir@mskcc.org.United States
- 文献类型
- 综述
- 期刊
- Current oncology reports2022 Mar
- 原文标识
- PubMed 35138599 · DOI 10.1007/s11912-022-01206-2