CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题：Pathological complete response of renal cell carcinoma with vena cava tumor thrombus to neoadjuvant TKI/IO combination therapy.
Pathological complete response of renal cell carcinoma with vena cava tumor thrombus to neoadjuvant TKI/IO combination therapy.
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
一名79岁女性被诊断为右肾肿瘤伴下腔静脉II级癌栓。术前接受avelumab联合axitinib治疗3个月。随后，她接受了肾切除术和癌栓取出术。组织学上，原发肿瘤和癌栓均无存活细胞，表明术前酪氨酸激酶抑制剂/免疫肿瘤联合治疗达到了病理完全缓解。免疫组织学检查显示，肿瘤栓塞区域的TIL（肿瘤浸润淋巴细胞）染色非常强，其中CD8占优势，超过CD4。
A 79-year-old female was diagnosed with a right renal tumor with a level II tumor thrombus of the vena cava. presurgical therapy was initiated with a combination of avelumab and axitinib for 3 monthes. Then, she underwent nephrectomy and thrombectomy.
Histologically, the primary tumor and tumor thrombus had no viable cells, indicating that pathological complete response was achieved with presurgical tyrosine kinase inhibitor/Immuno-oncology combination therapy. An immunohistological xamination showed very strong staining for tumor-infiltrating lymphocytes in the embolized area of the tumor, with CD8 predominating over CD4.
在 PubMed 查看 → 出版商原文（DOI） 全文 PDF（PMC）· 可下载 治疗专题与资料阅读指南 资料来源与翻译说明 报告译文或资料问题 →
MEMBER ACCOUNT
登录成功会直接打开下一页。
