中文摘要
癌症正在成为发达国家和发展中国家最致命的疾病之一,人们不断努力寻找创新疗法,以应对侵袭人体的多种类型癌症。随着时间推移,癌症的治疗选择呈指数级增长,但我们距离找到一种能够帮助治愈癌症的灵丹妙药仍有很长的路要走,而且基于当前证据,我们可能永远无法找到一种万能治愈方法,因此我们必须持续创新并找到多种方式来对抗这一可怕疾病的威胁,这一点变得至关重要。许多患者会出现疾病复发,需要二线治疗,或在某些情况下需要超过两线的治疗。在这篇综述文章中,我们讨论了现有疗法以及癌症治疗中取得的新进展。所讨论的各种癌症治疗的最新进展包括使用 CRISPR/Cas9 的基因编辑、诊疗一体化、病毒介导疗法、人工智能、TIL(肿瘤浸润淋巴细胞)疗法等。
展开英文摘要原文
Cancer is becoming one of the deadliest disease in both developed as well as developing countries and continuous effort is being made to find innovative therapies for myriad types of cancers that afflict the human body. Therapeutic options for cancer have grown exponentially over the time but we are quite a way off from finding a magic bullet that can help cure cancer and based on the current evidence we may never find a catch all cure ever and it becomes crucial that we keep on innovating and find multiple ways to attack the menace of this dreaded disease.
Many patients suffer recurrence of disease and require second-line or in some cases more than two lines of treatment. In this review article we have discussed the available therapies along with the newer advancements that have been made in cancer therapy. Latest developments in treatment of various cancers that have been discussed include gene editing using CRISPR/Cas9, theranostics, viral mediated therapy, artificial intelligence, tumor infiltrating lymphocyte therapy, etc.
论文信息
- 作者
- Malik D、Mahendiratta S、Kaur H、Medhi B
- 第一作者单位
- Department of Biochemistry, All India Institute of Medical Sciences, Bilaspur, India.India
- 通讯作者单位
- Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India. Electronic address: drbikashus@yahoo.com.India
- 文献类型
- 综述
- 期刊
- Gene2021 Dec 30