ROR1 CAR-T 细胞与铁死亡诱导剂通过 PC-PUFA2 协同调控肿瘤铁死亡
ROR1 CAR-T cells and ferroptosis inducers orchestrate tumor ferroptosis via PC-PUFA2.
将 ROR1 CAR-T 细胞与铁死亡诱导剂联合应用,通过增加脂质过氧化促进铁死亡,从而增强了对 NSCLC 的抗肿瘤疗效。
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FOR TREATMENT
现在就能报名的(招募中)排在最前,共 0 项。同一状态内中国中心优先。信息来自 ClinicalTrials.gov 与 CDE 公开登记。能否入组、费用与可及性,以登记原文和主治医生判断为准。
FOR RESEARCH
ROR1 CAR-T cells and ferroptosis inducers orchestrate tumor ferroptosis via PC-PUFA2.
将 ROR1 CAR-T 细胞与铁死亡诱导剂联合应用,通过增加脂质过氧化促进铁死亡,从而增强了对 NSCLC 的抗肿瘤疗效。
RORing CAR T Cells in Solid and Hematologic Cancers: Same but Different.
Phase I Study of ROR1-Specific CAR-T Cells in Advanced Hematopoietic and Epithelial Malignancies.
ROR1 CAR-T 细胞在大多数患者中耐受良好。
CAR-T therapy in non-small cell lung cancer: Clinical prospects, potential, and strategies for cardiotoxicity management.
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