B7-H3 在肉瘤中的临床与治疗相关性:来自系统综述的分子见解
Clinical and Therapeutic Relevance of B7-H3 in Sarcomas: Molecular Insights from a Systematic Review.
肉瘤是一组异质性间叶源性恶性肿瘤,以显著的形态学和分子学多样性为特征。
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
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登记显示招募中的试验排在最前,共 4 项。同一状态内中国中心优先;具体中心是否开放须核实。信息来自 ClinicalTrials.gov、CDE 与 ChiCTR 公开登记。能否入组、费用与可及性,以登记原文和主治医生判断为准。
FOR RESEARCH
Clinical and Therapeutic Relevance of B7-H3 in Sarcomas: Molecular Insights from a Systematic Review.
肉瘤是一组异质性间叶源性恶性肿瘤,以显著的形态学和分子学多样性为特征。
Assessment of Clinical and Immunological Factors of Local Recurrence in Canine Soft Tissue Sarcoma.
A partial response to atezolizumab in alveolar soft part sarcoma with near-complete resolution of extensive pulmonary metastases: a case report.
Immunotherapy-based salvage therapy in advanced soft tissue sarcoma after first-line chemotherapy: a retrospective single-center analysis with emphasi
基于免疫治疗的方案,尤其是化学免疫治疗,在晚期 STS 中显示出较传统化疗有 PFS 获益的提示,其中 UPS 显示出与疾病控制相关的提示。安全性特征可接受。然而,回顾性设计、历史对照、样本量有限以及总生存期数据不成熟等固有局限性,需要谨慎解读。
Targeted antibody-drug conjugates for rhabdomyosarcoma and other FGFR4-expressing cancers.
Proteomics-based approach reveals the involvement of spliceosomal components SF3B and SerpinB9 in dermatofibrosarcoma protuberans.
SerpinB9 过表达与 DFSP 的纤维肉瘤样特征相关,可能是一个候选预后生物标志物。
Optimized L1CAM-CAR T cells enhance activity against moderate-antigen-density rhabdomyosarcoma models.
Restoring STING expression in soft tissue sarcoma increases activation and function of tumor-infiltrating lymphocytes.
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