拉丁美洲 CAR-T 治疗的可及性:障碍、缺口与前进路径
Access to CAR-T therapy in Latin America: Barriers, gaps, and pathways forward.
我们得出结论,在拉丁美洲实现公平的CAR-T细胞可及性需要多方面的策略:协调一致的监管框架、可扩展的学术制造、基础设施投资以及整合人群特异性免疫基因组学分析。
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按「中国试验优先 → 正在招募 → 更新更近」排序。信息来自 ClinicalTrials.gov 与 CDE 公开登记。能否入组、费用与可及性,以登记原文和主治医生判断为准。
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Access to CAR-T therapy in Latin America: Barriers, gaps, and pathways forward.
我们得出结论,在拉丁美洲实现公平的CAR-T细胞可及性需要多方面的策略:协调一致的监管框架、可扩展的学术制造、基础设施投资以及整合人群特异性免疫基因组学分析。
Engineering CLL-1 CAR-NK cells via mRNA-LNP for potent antitumor activity and reversal of HLA-E-mediated resistance in acute myeloid leukemia.
瞬时、非整合的 mRNA LNP 转染的 CLL-1 CAR-NK 细胞为 MDR AML 提供了一种安全有效的策略。
Distinct effector functions and synergy of CAR mRNA-engineered T cells and macrophages in the clearance of CD19(+) leukemia cells.
我们的研究结果凸显了 CAR-T 细胞优越的肿瘤细胞杀伤能力。
Advances in Nanotechnology for Lymphoma Treatment: Targeted Delivery, Immunomodulation, and TME-Responsive Therapy Strategies.
淋巴瘤是一种异质性淋巴细胞恶性增殖性疾病,兼具液体肿瘤和实体肿瘤的特征。
Vaccine-induced T-cell responses against SARS-CoV-2 and its Omicron variant in patients with B cell-depleted lymphoma after CART therapy.
这些数据强调了在CD19 CAR-T细胞治疗后接种COVID-19疫苗的重要性,即使存在长期B细胞发育不全。
Enhanced BNT162b2 vaccine-induced cellular immunity in anti-CD19 CAR T cell-treated patients.
这些数据强调了在CD19 CAR-T细胞治疗后接种COVID-19疫苗的重要性,即使存在长期B细胞发育不全。
Safety and efficacy of the mRNA BNT162b2 vaccine against SARS-CoV-2 in five groups of immunocompromised patients and healthy controls in a prospective
结果显示,mRNA BNT162b2 疫苗在免疫功能低下患者中是安全的。
Humoral and T-cell immune responses to coronavirus disease 2019 vaccines in patients with hematological malignancies.
本研究提供了确证性真实世界证据,表明CD19恢复是体液应答的关键决定因素,而疫苗诱导的T细胞免疫即使在抗体无应答者中也可能得以保留,支持在这一高风险人群中继续开展疫苗接种工作。
Revolutionizing Cancer Treatment: Recent Advances in Immunotherapy.
肿瘤免疫治疗已成为肿瘤学中一种变革性方法,利用机体免疫系统特异性靶向并摧毁恶性细胞。
Infectious complications following CAR-t cell therapy for B cell non-Hodgkin lymphoma: a single-center experience and review of the literature.
我们评估了本机构48例接受CAR-T细胞治疗后R/R B细胞NHL患者的ICs。
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