一种多功能的自我扩增 mRNA 系统将溶瘤病毒的优势整合到单一灵活的骨架上,用于癌症治疗
A versatile self-amplifying mRNA system consolidates oncolytic virus benefits into a single flexible backbone for cancer therapy.
溶瘤病毒(OVs)代表了一种有前景的癌症免疫治疗手段;然而,其临床转化受到生产复杂性、生物安全问题、预存中和抗体以及病毒基因组工程限制的显著阻碍。
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A versatile self-amplifying mRNA system consolidates oncolytic virus benefits into a single flexible backbone for cancer therapy.
溶瘤病毒(OVs)代表了一种有前景的癌症免疫治疗手段;然而,其临床转化受到生产复杂性、生物安全问题、预存中和抗体以及病毒基因组工程限制的显著阻碍。
Dendritic cells in cancer immunotherapy: functional barriers, reprogramming strategies and translational challenges.
癌症免疫治疗依赖于有效的抗原呈递和T细胞激活。
Combination therapy with oncolytic virus and T cells or mRNA vaccine amplifies antitumor effects.
基于过继转移T细胞或溶瘤病毒的抗肿瘤疗法近年来取得了显著进展,但其对实体瘤的浸润效率有限,单独使用时难以达到理想的抗肿瘤效果。
Nanomedicine for advanced cancer immunotherapy.
免疫治疗已成为一种强大的策略,用于治疗液体肿瘤,以克服传统癌症疗法的局限性。
Advances and challenges in cancer immunotherapy: Strategies for personalized treatment.
癌症免疫疗法通过利用免疫系统特异性靶向癌细胞,彻底改变了肿瘤学领域,与传统疗法相比,其全身毒性更低。
New Standards in the Treatment of Advanced Metastatic Melanoma: Immunotherapy and BRAF-Targeted Therapies as Emerging Paradigms.
尽管皮肤黑色素瘤仅占皮肤癌的约 2%,但其快速进展使其成为一种高死亡率的侵袭性皮肤癌。
Advancements in Melanoma Treatment: A Review of PD-1 Inhibitors, T-VEC, mRNA Vaccines, and Tumor-Infiltrating Lymphocyte Therapy in an Evolving Landsc
黑色素瘤是一种侵袭性皮肤癌,治疗难度很大。
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