IDR 诱导的 CAR 凝聚增强 CAR-T 对低抗原癌症的细胞毒性
IDR-induced CAR condensation improves the cytotoxicity of CAR-Ts against low-antigen cancers.
我们的工作表明,IDR 是通过诱导生物分子凝聚来改善 CAR-T 功能的新工具集。
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IDR-induced CAR condensation improves the cytotoxicity of CAR-Ts against low-antigen cancers.
我们的工作表明,IDR 是通过诱导生物分子凝聚来改善 CAR-T 功能的新工具集。
Expression of CD22 in Triple-Negative Breast Cancer: A Novel Prognostic Biomarker and Potential Target for CAR Therapy.
我们首次证实 CD22 在三阴性乳腺癌(TNBC)中高表达。
A Bibliometric and Knowledge-Map Analysis of CAR-T Cells From 2009 to 2021.
作为一种具有巨大潜力和临床应用前景的抗肿瘤疗法,CAR-T细胞疗法仍处于快速发展阶段。CAR-T细胞相关领域在未来仍将是研究热点。
Updated Clinical Perspectives and Challenges of Chimeric Antigen Receptor-T Cell Therapy in Colorectal Cancer and Invasive Breast Cancer.
近年来,结直肠癌(CRC)和乳腺癌(BC)的发病率在全球范围内上升,并因缺乏选择性抗肿瘤疗法而导致更高的死亡率。
IDR-induced CAR condensation improves the cytotoxicity of CAR-Ts against low-antigen cancers.
基于嵌合抗原受体(CAR)T 细胞的疗法在治疗其他方法难以治愈的癌症、尤其是 B 细胞恶性肿瘤方面显示出显著疗效。
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