TIL(肿瘤浸润淋巴细胞)与乳腺放疗:国际免疫肿瘤生物标志物工作组展望
Tumour-infiltrating lymphocytes and breast radiotherapy: perspectives from the International Immuno-Oncology Biomarker Working Group.
TIL(肿瘤浸润淋巴细胞)(TILs)是乳腺癌的预后和预测生物标志物。
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Tumour-infiltrating lymphocytes and breast radiotherapy: perspectives from the International Immuno-Oncology Biomarker Working Group.
TIL(肿瘤浸润淋巴细胞)(TILs)是乳腺癌的预后和预测生物标志物。
Advances in TIL therapy: Expanding the horizons beyond melanoma.
TIL(肿瘤浸润淋巴细胞)疗法代表着实体瘤治疗的突破,满足了选择有限患者的未满足需求。
A prognostic and predictive computational pathology immune signature for ductal carcinoma in situ: retrospective results from a cohort within the UK/A
高 TIL 密度与更高的复发风险相关——尤其是浸润性复发——并且与 DCIS 患者更大的放疗获益相关。我们基于 TIL 的计算病理学特征在 DCIS 中具有预后和预测作用。
Tumor-Infiltrating Lymphocytes and Preoperative Partial Breast Irradiation in Early-Stage Breast Cancer: Insights From the Prospective PAPBI Cohort.
在这一接受术前部分乳腺照射的早期乳腺癌患者队列中,纵向评估显示RT后sTILs变化极小。在达到pCR的患者中,我们观察到其基线sTILs显著高于未达到pCR的患者。
Isolation of a tumor neoantigen specific CD8+ TCR from a skin biopsy of a vaccination site.
我们的研究首次表明,肿瘤突变特异性T细胞在疫苗接种部位以高频率产生,并可通过标准方法分离用于TCR筛选。
Immunotherapies for Breast Cancer: From Checkpoint Inhibition to Emerging Cellular Therapies.
乳腺癌仍是全球癌症相关发病率和死亡率的主要原因,其治疗反应受每种乳腺癌亚型独特生物学特征的影响。
Tumor-Infiltrating lymphocyte dynamics as biomarkers of neoadjuvant treatment response in luminal breast cancer.
基线TIL水平及化疗引起的TIL下降与HR+/HER2乳腺癌新辅助化疗的病理缓解强烈相关。尽管TIL动态变化可能作为治疗疗效的替代标志物,但其在该亚型中对长期结局的预测价值有限。需要更大规模、设计良好的前瞻性研究来进一步阐明这一关系。
Making sense of TILs: recommendations for morphological assessment of tumour-infiltrating lymphocytes in gastro-oesophageal carcinoma: A report on beh
在癌症免疫检查点抑制剂时代,寻找能够识别最可能实现持久缓解患者的预后生物标志物的需求日益迫切。
Tumor-Infiltrating Lymphocytes in Breast and Female Genital Tract Cancers: Overlooked Potential and Unexplored Frontiers.
基于TIL的疗法在个体化免疫治疗中显示出潜力,尤其是在复发、难治性卵巢癌中。对较罕见妇科肿瘤的研究有限,阻碍了更广泛的临床应用。
Negative Relationship between Post-Treatment Stromal Tumor-Infiltrating Lymphocyte (TIL) and Survival in Triple-Negative Breast Cancer Patients Treate
我们的结果表明,NAC后TIL富集的TNBC患者复发风险更高。
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