没有 BCMA？没问题：靶向 CD70 的 CAR-NK 细胞在高危骨髓瘤中展现前景
No BCMA? No Problem: A CD70-Targeting CAR-NK Cell Shows Promise in High-risk Myeloma.
79.4分
★★★★☆
站内排序·非疗效
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
FRONTIER PAPERS
前沿论文 7
靶向 CD70 的 CAR-NK 细胞克服 BCMA 下调并改善高危多发性骨髓瘤模型中的生存
CD70-Targeting CAR NK Cells Overcome BCMA Downregulation and Improve Survival in High-risk Multiple Myeloma Models.
79.4分
★★★★☆
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CD28 共刺激经 LCK/CD3ζ/ZAP70 信号轴增强 NK 细胞中的 CAR 信号传导
CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis.
64.7分
★★★☆☆
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CD70 是 EMT 相关 EGFR 酪氨酸激酶抑制剂耐药中上调的治疗靶点
CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance.
62.9分
★★★☆☆
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非病毒 TcBuster 转座子工程化 CD70-CAR NK 细胞治疗骨肉瘤
Non-viral TcBuster transposon engineering of CD70-CAR natural killer cells for the treatment of osteosarcoma.
59.2分
★★★☆☆
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嵌合抗原受体自然杀伤（CAR-NK）细胞治疗乳腺癌的疗效与安全性评价：系统综述与荟萃分析
Evaluation of Efficacy and Safety of Chimeric Antigen Receptor-Natural Killer (CAR-NK) Cells in Breast Cancer: A Systematic Review and Meta-Analysis.
54.1分
★★★☆☆
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面向血液肿瘤与实体瘤免疫治疗的高效、无自相残杀的非病毒工程化 CD70 靶向 CAR NK 细胞
Efficient, fratricide free non-viral engineering of CD70-targeted CAR NK cells for hematologic and solid tumor immunotherapy.
35.1分
★★☆☆☆
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