代谢依赖性与神经祖细胞失调:儿童高级别胶质瘤发生的驱动力
Metabolic dependencies and neural progenitor dysregulation: driving forces in paediatric high-grade glioma development.
儿童高级别胶质瘤(pHGGs)是儿童中最致命的脑肿瘤,其特征是深刻的表观遗传失调和有限的治疗选择。
FRONTIER PAPERS
Metabolic dependencies and neural progenitor dysregulation: driving forces in paediatric high-grade glioma development.
儿童高级别胶质瘤(pHGGs)是儿童中最致命的脑肿瘤,其特征是深刻的表观遗传失调和有限的治疗选择。
Immunotherapy for Cancer: Current Advances and Future Directions.
免疫治疗为多种癌症的治疗带来了根本性转变,为癌症患者带来了希望。
Advancing chimeric antigen receptor T-cell therapy frontiers in glioblastoma: Navigating the current landscape from clinical hurdles to breakthrough s
胶质母细胞瘤(GBM)是一种致死性脑肿瘤,标准治疗下预后不佳,其全球发病率不断上升,凸显了对新型治疗方法的迫切需求。
Oncolytic virotherapy at the tumor microenvironment-CAR Therapy interface: Mechanisms, clinical translation, and future directions.
溶瘤病毒疗法已从一种肿瘤选择性溶细胞策略演变为一种可编程的免疫治疗平台,能够重塑肿瘤微环境(TME)。
Immune response recalibration using immune therapy and biomimetic nano-therapy against high-grade gliomas and brain metastases.
尽管采用了手术切除、化疗和放疗等积极的标准治疗,高级别胶质瘤(HGGs)和脑转移(BM)的治疗在二十多年里仍具挑战性。
Pathway dysregulation and therapeutic resistance in glioblastoma: molecular mechanisms and emerging therapeutic targets.
本综述进一步探讨了治疗耐药性的潜在机制以及当前靶向治疗的局限性。
The intrinsic and microenvironmental features of diffuse midline glioma: Implications for the development of effective immunotherapeutic treatment str
弥漫性中线胶质瘤(DMG),包括脑干型(弥漫性内生性脑桥胶质瘤),是儿童中枢神经系统(CNS)肿瘤。
Shaping immunotherapy through the tumor microenvironment: Translational perspectives.
肿瘤微环境(TME)是癌症进展的协调者,也是免疫治疗耐药的主要介导者。
Harnessing dendritic cells (DCs) for melanoma immunotherapy: From basic biology to clinical strategies.
黑色素瘤作为一种免疫原性皮肤癌,是癌症免疫治疗中备受关注的领域。
Overcoming resistance in glioblastoma immunotherapy: lessons from the past and opportunities for the future.
胶质母细胞瘤(GBM)是成人中侵袭性最强的原发性脑肿瘤,其特征为快速增殖、弥漫性浸润和强烈的治疗耐药,即使接受最大程度治疗,中位生存期仍约为 15 个月。
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