CELL INTELLIGENCE · 肿瘤细胞治疗研究

CD19-CAR-T 细胞在儿童、青少年及年轻成人 B 细胞急性淋巴细胞白血病患者脑脊液中的长期存续

CD19-CAR T cells persist long-term in the cerebrospinal fluid of pediatric, adolescent and young adult patients with B-cell acute lymphoblastic leukem

白细胞单采时外周原始细胞是儿童和年轻成人接受 tisagenlecleucel 后生存的风险因素

Peripheral Blasts at Apheresis as a Risk Factor for Survival following Tisagenlecleucel in Children and Young Adults.

Tisagenlecleucel 在复发/难治性 ALL 儿童及年轻成人患者中的长期临床结局

Long-Term Clinical Outcomes of Tisagenlecleucel in Pediatric and Young Adult Patients With Relapsed/Refractory ALL.

脑室内 B7-H3 靶向 CAR-T 细胞治疗非脑桥 DMG 与复发/难治性儿童中枢神经系统肿瘤：I 期试验

Intracerebroventricular B7-H3-targeting CAR T cells for non-pontine DMG and recurrent/refractory pediatric CNS tumors: a phase 1 trial.

重复 ICV B7-H3 CAR-T 细胞给药在多种儿童 CNS 肿瘤中可行且可耐受，支持在未来试验中继续研究。

儿童 B-ALL 中 CAR-T 后 HLH 样综合征与死亡风险增加及 CD19 阴性复发相关

HLH-like syndromes associate with increased risk of death and CD19-negative relapse post-CAR T in pediatric B-ALL.

靶向 IL7 受体的 CAR-T 细胞疗法治疗 T 细胞急性淋巴细胞白血病

IL7-Receptor-Targeted CAR T-Cell Therapy for T-Cell Acute Lymphoblastic Leukemia.

FATP2 介导的脂质代谢增强 B 细胞急性淋巴细胞白血病中 CAR-T 细胞治疗的耐药

FATP2-mediated lipid metabolism enhances chimeric antigen receptor T-cell therapy resistance in B-cell acute lymphoblastic leukemia.

儿童鼻外 EBV 阴性结外 NK/T 细胞淋巴瘤；病例报告

Pediatric extranasal, EBV-negative, extranodal natural killer/T-cell lymphoma; case report.

儿童和年轻成人原发性中枢神经系统肿瘤的 CAR-T 细胞疗法：早期临床试验的系统综述，重点关注弥漫性中线胶质瘤

Chimeric Antigen Receptor-T Cell Therapy for Pediatric and Young Adult Primary Central Nervous System Tumors: A Systematic Review of Early Phase Clini

初步临床经验表明，针对儿童和年轻成人 CNS 肿瘤的 CAR-T 细胞疗法具有生物学活性且临床可行，其毒性特征独特但可控。

CD19/CD22 双价 CAR-T 细胞治疗儿童、青少年与年轻成人 B-ALL：1 期试验最终结果

CD19/CD22 bivalent CAR T cells in children, adolescents and young adults with B-ALL: final phase 1 trial results.