CELL INTELLIGENCE · 肿瘤细胞治疗研究

实体瘤 CAR-T 细胞治疗安全性的深入分析

In-depth analysis of the safety of CAR-T cell therapy for solid tumors.

缺氧条件下间充质干细胞来源外泌体的促肿瘤效应及治疗意义：一项系统综述

Pro-tumorigenic effects and therapeutic implications of mesenchymal stem cell-derived exosomes under hypoxic conditions: a systematic review.

当前研究表明，间充质干细胞来源的外泌体经低氧预处理后，能够影响癌细胞中的特定基因、miRNA 及信号通路，从而促进增殖、迁移和侵袭，并抑制凋亡。

T 细胞耗竭的当前研究现状与新兴前沿图谱：一项基于数据挖掘的综合研究

Mapping Current Research Status and Emerging Frontiers of T-Cell Exhaustion: A Comprehensive Data-Mining-Based Study.

本研究是首次对 2005 至 2024 年间聚焦 Tex 的文献开展广泛的文献计量学评估。

非肿瘤药物（美替拉酮）与表观遗传抑制剂协同显示出抗癌能力，并似乎被动参与靶向癌细胞

Non-oncology drug (meticrane) shows anti-cancer ability in synergy with epigenetic inhibitors and appears to be involved passively in targeting cancer

分泌 B7H3 靶向 BiTE 的 GPC3 靶向 CAR-T 细胞在体外实验中展现对肝细胞癌细胞的强效细胞毒性活性

GPC3-targeted CAR-T cells secreting B7H3-targeted BiTE exhibit potent cytotoxicity activity against hepatocellular carcinoma cell in the in vitro assa

多发性骨髓瘤髓外复发表现为肝脏占位性病变，接受 daratumumab、pomalidomide、dexamethasone 和 bendamustine 治疗

Extramedullary relapse of multiple myeloma presenting as space-occupying lesion in liver treated with daratumumab, pomalidomide, dexamethasone and ben