肿瘤来源的细胞外囊泡在 NK 细胞免疫逃逸中的作用:分子机制与治疗启示
Cancer-derived extracellular vesicles in natural killer cell immune evasion: Molecular mechanisms and therapeutic insights.
NK 细胞是先天淋巴细胞,具备快速识别和消灭癌细胞的能力。
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Cancer-derived extracellular vesicles in natural killer cell immune evasion: Molecular mechanisms and therapeutic insights.
NK 细胞是先天淋巴细胞,具备快速识别和消灭癌细胞的能力。
Parallel processing of T cells and natural killer cells to enhance in vivoCAR T cell activity against blood and solid cancers.
本研究鼓励优化利用白细胞单采产物。通过将废弃的PBMC回收为NK细胞,可有效增强CAR T细胞疗法,改善肿瘤清除率和生存率。
KLRC1 knockout overcomes HLA-E-mediated inhibition and improves NK cell antitumor activity against solid tumors.
我们的结果表明,敲除 KLRC1 是提高 NK 细胞对 HLA-E⁺ 肿瘤抗肿瘤活性的有效策略,并可应用于实体瘤 NK 细胞疗法的开发。
Next Generation CD44v6-Specific CAR-NK Cells Effective against Triple Negative Breast Cancer.
有必要开发针对三阴性乳腺癌(TNBC)的新有效疗法。
NK3.3-Derived Extracellular Vesicles Penetrate and Selectively Kill Treatment-Resistant Tumor Cells.
癌症治疗常因肿瘤耐药性的产生而失效,进而导致转移和复发。
Mesothelin-targeted CAR-NK Cells Derived From Induced Pluripotent Stem Cells Have a High Efficacy in Killing Triple-negative Breast Cancer Cells as Sh
免疫疗法的出现为癌症治疗引入了一种有前景的新型方法。
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