结外自然杀伤/T 细胞淋巴瘤:从致命到可治愈
Extranodal natural killer/T-cell lymphoma: From fatal to curable.
尽管近 80% 的新诊断 ENKTCL 患者可获得长期生存,但复发/难治性 ENKTCL 的治疗依然至关重要。
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按「中国试验优先 → 正在招募 → 更新更近」排序。信息来自 ClinicalTrials.gov 与 CDE 公开登记。能否入组、费用与可及性,以登记原文和主治医生判断为准。
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Extranodal natural killer/T-cell lymphoma: From fatal to curable.
尽管近 80% 的新诊断 ENKTCL 患者可获得长期生存,但复发/难治性 ENKTCL 的治疗依然至关重要。
Phase 1 Study of KITE-222, an Autologous CLL-1-Directed CAR T-cell Therapy in Patients with Relapsed/Refractory Acute Myeloid Leukemia.
尽管生产成功且安全性可接受,KITE-222缺乏初步疗效,需要未来研究解决CLL-1异质性并着重改善体内扩增和抗肿瘤活性。
The search for safe and effective CAR-T targets in AML.
急性髓系白血病(AML)仍是一种高度侵袭性的恶性肿瘤,治疗选择有限,长期生存较差。
Sequencing CD19-targeted therapies in patients with relapsed/refractory large B-cell lymphoma: A narrative review.
CD19在早期阶段即表达于B细胞,并在大多数B细胞恶性肿瘤中表达,但在造血干细胞或其他正常组织中不表达,因此使其成为治疗复发或难治性(R/R)大B细胞淋巴瘤患者的一个有吸引力的治疗靶点。
Progress in reprogramming failed graft-versus-leukemia immunity in acute myeloid leukemia relapse after allogeneic transplantation.
急性髓系白血病(AML)异基因造血干细胞移植(allo-HSCT)后复发影响40-50%的受者,并且仍然是移植后死亡的主要原因;中位总生存期约为5个月,1年生存率低于20%。
Pre-CAR-T B-cell-directed immunotherapy exposure and outcomes after CD19 CAR-T for large B-cell lymphoma: An EBMT registry analysis.
Novel targeted therapy and cellular immunotherapy enabling allogeneic hematopoietic stem cell transplantation for relapsed/refractory acute myeloid le
复发或难治性(R/R)急性髓系白血病(AML)患者的预后极差。
Response kinetics following CAR T-cell therapy for large B-cell lymphoma: a LYSA study from the DESCAR-T registry.
M1 处的不完整响应不应自动提示观察并等待。
Real-world CAR-T practice patterns in patients with mantle cell lymphoma: an international survey on behalf of the EBMT lymphoma working party.
Racial and ethnic disparities in brain-to-vein time among patients receiving CD19 CAR-T cell therapy for relapsed/refractory DLBCL.
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