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肿瘤学中人工智能的新兴进展:2026 AACR 年会最新更新

英文原题:Emerging artificial intelligence advances in oncology: latest updates from the 2026 AACR annual meeting.

查看英文原题

Emerging artificial intelligence advances in oncology: latest updates from the 2026 AACR annual meeting.

PubMed 2026/07/03(内容时间) J Hematol Oncol Q1 · IF 47.8(JCR 2025)

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中文摘要

2026年美国癌症研究协会(AACR)年会展示的进展表明,肿瘤学人工智能(AI)正从独立模型转向整合式智能体系统。Synapse等平台支持大规模数据协调,促进可互操作且可重复的研究。在此基础上,DrBioRight、GP CoPilot和Isabl AI Agent等对话式及多智能体AI工具,可通过自然语言与多模态癌症数据交互,降低技术门槛。用于真实世界数据(RWD)转化的智能体框架,包括临床文档抽取、队列提取和健康社会决定因素(SDOH)分析,展现出较高准确性和可扩展性;自我批判系统则有助于提高可靠性。在临床方面,AI通过经验证的影像生物标志物、改进试验匹配和可扩展队列识别,发挥越来越大的作用。与此同时,多智能体系统正在加速治疗发现,包括CAR-T 开发和免疫治疗靶点识别。总体而言,这些进展使AI成为癌症研究和精准肿瘤学中的积极协作伙伴。

展开英文摘要原文

Advances presented at the 2026 American Association for Cancer Research (AACR) Annual Meeting highlight a shift from standalone artificial intelligence (AI) models to integrated, agentic systems across oncology. Platforms such as Synapse enable large-scale data coordination, supporting interoperable and reproducible research. Building on this foundation, conversational and multi-agent AI tools (e. g. , DrBioRight, GP CoPilot, Isabl AI Agent) allow natural language interaction with multimodal cancer data, lowering technical barriers.

Agentic frameworks for real-world data (RWD) transformation, including clinical document abstraction, cohort extraction, and social determinants of health (SDOH) analysis, demonstrate high accuracy and scalability, while self-critical systems improve reliability.

Clinically, AI shows growing impact through validated imaging biomarkers, enhanced trial matching, and scalable cohort identification. In parallel, multi-agent systems are accelerating therapeutic discovery, including CAR-T development and immunotherapy target identification. Collectively, these advances position AI as an active, collaborative partner in cancer research and precision oncology.

论文信息

作者
Li YR、Shao Z、Nan H
单位
Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, CA, USA. charlie.li@ucla.edu.United States
文献类型
会议论文集 · 读者来信
期刊
Journal of hematology & oncology2026 Jul 3
原文标识
PubMed 42400083 · DOI 10.1186/s13045-026-01823-5