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通过 CD19CAR-T 细胞疗法联合第三代酪氨酸激酶抑制剂在伴有费城染色体的急性不确定谱系白血病中实现持久深度分子缓解:为不适合移植患者提供的一种潜在策略

英文原题:Durable deep molecular response via CD19 chimeric antigen receptor T-cell therapy combined with a third-generation tyrosine kinase inhibitor in acute leukemia of ambiguous lineage with the Philadelphia chromosome: a potential strategy for transplant-ineligible patients.

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Durable deep molecular response via CD19 chimeric antigen receptor T-cell therapy combined with a third-generation tyrosine kinase inhibitor in acute leukemia of ambiguous lineage with the Philadelphia chromosome: a potential strategy for transplant-ineligible patients.

PubMed 2026/04/16(内容时间) Haematologica Q1 · IF 8.2(JCR 2025)

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摘要

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论文信息

作者
Zhang A、Gong B、Liu Y、Zhang G、Zhou C、Li S、Guo C、Yang H
第一作者单位
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China; Tianjin Institutes of Health Science, Tianjin.China
通讯作者单位
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China; Tianjin Institutes of Health Science, Tianjin. qiushaowei@ihcams.ac.cn.China
期刊
Haematologica2026 Sep 1
原文标识
PubMed 41988760 · DOI 10.3324/haematol.2026.300521