CAR-T(CAR-T)细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题:A Pluripotent Road to Immunoengineering.
A Pluripotent Road to Immunoengineering.
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
过继性免疫治疗,尤其是CAR-T 细胞,在过去十年中治疗血液系统恶性肿瘤取得了相当大的成功。然而,患者来源细胞工程化的变异性、时间投入和高成本限制了其应用。人类多能干细胞可能为这些问题提供一种现成的、更便宜且可扩展的解决方案。
Adoptive immunotherapy, particularly chimeric antigen receptor T cells, has achieved considerable success in treating hematologic malignancies over the past decade. However, variability, time commitment and high cost for engineering patient-derived cells have limited their application. Human pluripotent stem cells could provide an off-the-shelf, cheaper and scalable solution to these issues.
在 PubMed 查看 → 出版商原文(DOI) 全文 PDF(PMC)· 可下载 治疗专题与资料阅读指南 资料来源与翻译说明 报告译文或资料问题 →
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