CAR-T(CAR-T)细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CAR-T(CAR-T)细胞在血液系统恶性肿瘤中的应用推动了这种免疫治疗形式的显著进展。
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题:Blinatumomab nonresponse correlates with poor survival after brexucabtagene autoleucel in B-cell ALL.
Blinatumomab nonresponse correlates with poor survival after brexucabtagene autoleucel in B-cell ALL.
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在一项针对复发/难治性B细胞急性淋巴细胞白血病的brexucabtagene autoleucel接受者(N = 278)的真实世界分析中,对先前blinatumomab无应答与随后CAR-T 细胞治疗结局显著更差相关。
In a real-world analysis of brexucabtagene autoleucel recipients with relapsed/refractory B-cell acute lymphoblastic leukemia (N = 278), lack of response to prior blinatumomab correlates with significantly worse following chimeric antigen receptor T-cell therapy outcomes.
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