CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题:Developing a Framework of Entrustable Professional Activities for Residency Training in Hematology.
Developing a Framework of Entrustable Professional Activities for Residency Training in Hematology.
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本研究通过整合本地临床需求(高患者量、资源受限)和多学科协作,弥补了全球 EPA 模型的不足,建立了中国首个血液学特异性 EPA 框架。该框架为基于胜任力的评估提供了经过验证的工具,未来步骤侧重于数字化实施和全国性验证。
可信任专业活动(EPAs)是胜任且安全的临床实践所必需的,可作为评估受训者是否准备好独立进行患者诊疗的里程碑。本研究旨在为中国血液科住院医师培训制定一个符合具体情境的EPA框架。
我们采用改良德尔菲法,纳入来自8家教学医院的35名专家,建立中国首个血液学特异性EPA框架。制定过程包括三个关键部分:(1)系统文献综述,将国际EPA模型与中国住院医师规范化培训(STSR)要求相结合;(2)通过EQual rubric进行结构验证(截断值:4.07);(3)两轮德尔菲咨询,评估重要性、可观察性、可评价性、可重复性、可行性及信任-监督水平。专家参与度指标和评分者间一致性用于评估共识质量。
初步的14项框架最终在排除“公共卫生应急响应”(EPA 14;平均分=3.23)和“告知坏消息”(EPA 13;57.1%的专家主张删除)后,精炼为12项EPAs。关键修订涉及将造血干细胞移植(HSCT)能力领域扩展至包含供者选择(EPA 7),以及因评估标准标准化不足而临时增加随后又删除“细胞免疫治疗并发症管理”。最终EPAs获得了全体一致的EQual合规性(≥4.07)和强烈的Delphi共识(Kendall's W:第1轮=0.271,第2轮=0.529,p<0.001)。临床委托-监督水平按培训阶段和毕业时预期能力进行了系统分层。
Entrustable professional activities (EPAs), essential for competent and safe clinical practice, serve as milestones to assess trainees' readiness for independent patient care. This study aimed to develop a context-specific EPA framework for hematology residency training in China.
We employed a modified Delphi method involving 35 experts from 8 academic hospitals to establish China's inaugural hematology-specific EPA framework. The development process comprised three key components: (1) a systematic literature review integrating international EPA models with China's the Standardized Training System for Residents (STSR) requirements; (2) structural validation through the EQual rubric (cut-off: 4.07); and (3) a two-round Delphi consultations evaluating importance, observability, evaluability, repeatability, feasibility and entrustment-supervision levels. Expert engagement metrics and inter-rater agreement evaluated consensus quality.
The preliminary 14-item framework was ultimately refined to 12 EPAs following the exclusion of "Public Health Emergency Response" (EPA 14; mean score=3.23) and "Imparting Bad News" (EPA 13; 57.1% experts advocated removing). Key revisions involved expanding the hematopoietic stem cell transplantation (HSCT) competency domain to include donor selection (EPA 7) and the provisional addition then subsequent removal of "Cellular Immunotherapy Complications Management" due to insufficient standardization of assessment criteria. The final EPAs achieved unanimous EQual compliance (≥4.07) and strong Delphi consensus (Kendall's W: Round 1 = 0.271, Round 2 = 0.529, p<0.001). Clinical entrustment-supervision levels were systematically stratified by training phase and expected competency at graduation.
This study has established China's first hematology-specific EPA framework by addressing gaps in global EPA models through integration of integrating local clinical demands (high patient volume, resource constraints) and multidisciplinary coordination. The framework provides a validated tool for competency-based assessment, with future steps focusing on digital implementation and nationwide validation.
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