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通过 FOXP3 工程化实现代谢重编程:增强实体瘤中 CAR-T 细胞疗效的新策略

英文原题:Metabolic reprogramming via FOXP3 engineering: A Novel strategy to enhance CAR-T cell efficacy in solid tumors.

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Metabolic reprogramming via FOXP3 engineering: A Novel strategy to enhance CAR-T cell efficacy in solid tumors.

PubMed 2025/07/03(内容时间) Cell Mol Immunol Q1 · IF 23.9(JCR 2025)

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摘要

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论文信息

作者
Li D、Qiang S、Li B
第一作者单位
Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Respiratory and Critical Care Medicine and Department of Thoracic Surgery of Ruijin Hospital, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. danli@shsmu.edu.cn.China
通讯作者单位
Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Respiratory and Critical Care Medicine and Department of Thoracic Surgery of Ruijin Hospital, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. binli@shsmu.edu.cn.China
期刊
Cellular & molecular immunology2025 Aug
原文标识
PubMed 40610630 · DOI 10.1038/s41423-025-01315-5