CAR-T(CAR-T)细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CAR-T(CAR-T)细胞在血液系统恶性肿瘤中的应用推动了这种免疫治疗形式的显著进展。
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题:Advancing CAR T-cell Therapies with Artificial Intelligence: Opportunities and Challenges.
Advancing CAR T-cell Therapies with Artificial Intelligence: Opportunities and Challenges.
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
人工智能有望通过优化各个环节改善CAR-T 细胞疗法结局,涵盖靶点识别、载体设计、细胞制备以及个体化、数据驱动的临床决策。本文重点介绍释放这一潜力所需的步骤,包括建立标准化、全面的数据存储库,以解决人工智能学习面临的障碍,例如数据异质性和患者隐私保护。
Artificial intelligence could enhance chimeric antigen receptor T-cell therapy outcomes through optimization of all steps, from target identification, vector design, and manufacturing to personalized data-driven clinical decisions. In this report, we highlight steps toward unlocking this potential, including the need for standardized, comprehensive data repositories as a way for addressing barriers to artificial intelligence learning, such as data heterogeneity and patient privacy.
在 PubMed 查看 → 出版商原文(DOI) 全文 PDF(PMC)· 可下载 治疗专题与资料阅读指南 资料来源与翻译说明 报告译文或资料问题 →
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