CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题:Recent advances in immunotherapy and its combination therapies for advanced melanoma: a review.
Recent advances in immunotherapy and its combination therapies for advanced melanoma: a review.
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黑色素瘤的发病率逐年上升,恶性程度高,预后差,其治疗一直备受关注。临床较多应用的免疫治疗有免疫检查点抑制剂、双特异性抗体、肿瘤疫苗、过继细胞转移疗法、溶瘤病毒疗法等。随着技术和试验的不断发展,除免疫单药治疗外,免疫治疗与放疗的联合治疗也显示出惊人的疗效。本文就晚期黑色素瘤免疫单药及联合治疗的研究进展进行综述,以期为晚期黑色素瘤的治疗策略提供新思路。
The incidence of melanoma is increasing year by year and is highly malignant, with a poor prognosis. Its treatment has always attracted much attention. Among the more clinically applied immunotherapies are immune checkpoint inhibitors, bispecific antibodies, cancer vaccines, adoptive cell transfer therapy, and oncolytic virotherapy.
With the continuous development of technology and trials, in addition to immune monotherapy, combinations of immunotherapy and radiotherapy have shown surprising efficacy. In this article, we review the research progress of immune monotherapy and combination therapy for advanced melanoma, with the aim of providing new ideas for the treatment strategy for advanced melanoma.
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