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血液系统与实体恶性肿瘤的新型 NK 细胞疗法:ASCO 2024 最新进展

英文原题:Novel natural killer cell-based therapies for hematologic and solid malignancies: latest updates from ASCO 2024.

查看英文原题

Novel natural killer cell-based therapies for hematologic and solid malignancies: latest updates from ASCO 2024.

PubMed 2024/07/29(内容时间) J Hematol Oncol Q1 · IF 47.8(JCR 2025)

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中文摘要

自然杀伤(NK)细胞疗法在治疗血液系统恶性肿瘤和实体瘤方面已取得巨大进展。其独特的作用机制不依赖抗原呈递来识别和清除肿瘤细胞,使其成为一种有前景的癌症免疫治疗方法。在本综述中,我们全面总结了来自2024年美国临床肿瘤学会(ASCO)年会的有关新型NK细胞疗法的最新临床数据,强调这些进展在革新血液系统恶性肿瘤和实体瘤治疗方面的潜力。

展开英文摘要原文

Natural killer (NK) cell-based therapies have made great progress in treating both hematological and solid tumors. Their unique mechanism of action does not rely on antigen presentation to recognize and eliminate tumor cells, making them a promising approach for cancer immunotherapy.

In this review, we present a comprehensive summary of the latest clinical data of the novel NK cell-based therapies from the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, highlighting the potential of these advancements to revolutionize the treatment of hematologic malignancies and solid tumors.

论文信息

作者
Gong X、Zhang L、He X、Yang J、Li X、Liu W、Zhang B、Tao Z
第一作者单位
Department of Clinical Laboratory, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310000, P.R. China.China
通讯作者单位
Department of Hematology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, P.R. China. qianwb@zju.edu.cn.China
文献类型
综述 · 读者来信 · 非美国政府资助研究
期刊
Journal of hematology & oncology2024 Jul 29
原文标识
PubMed 39075582 · DOI 10.1186/s13045-024-01575-0