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CAR-T 治疗的最新进展

英文原题:Recent Advances in CAR-T Therapy.

查看英文原题

Recent Advances in CAR-T Therapy.

PubMed 2024/01/01(内容时间) Cancer Control Q2 · IF 3.1(JCR 2025)

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中文摘要

CAR-T 细胞疗法用于治疗对标准疗法难治的血液系统恶性肿瘤。这是一种免疫疗法,通过对患者自身 T 细胞进行编程,使其能够攻击肿瘤细胞。本文讨论 CAR-T 细胞的制备流程、常见治疗副作用,以及治疗后新近显现的 T 细胞恶性肿瘤风险。

展开英文摘要原文

Chimeric antigen receptor T cell therapy is used to treat hematological malignancies which are refractory to standard therapy. It is a form of immunotherapy in which a patient's T cells are programmed to act against tumor cells. We discuss the process of manufacturing CAR-T cells, the common side effects of therapy, and the recent emerging risk of T-cell malignancies after treatment.

论文信息

作者
Ali MB
单位
University of Maryland Medical Center, Baltimore, MD, USA.United States
文献类型
社论
期刊
Cancer control : journal of the Moffitt Cancer Center2024 Jan-Dec
原文标识
PubMed 38910268 · DOI 10.1177/10732748241263713