CAR-T（CAR-T）细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CAR-T（CAR-T）细胞在血液系统恶性肿瘤中的应用推动了这种免疫治疗形式的显著进展。
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
2 例恶性视神经浸润患者接受 CAR-T 细胞治疗后的严重视力损害
英文原题：Severe Visual Impairment Following CAR T-Cell Therapy in Two Individuals with Malignant Optic Nerve Infiltration.
查看英文原题
Severe Visual Impairment Following CAR T-Cell Therapy in Two Individuals with Malignant Optic Nerve Infiltration.
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中文摘要
我们报告了 2 例患者在接受 CAR-T 细胞输注后出现局部眼部炎症。为处理由此导致的严重视力损害，两名患者均接受了全身性糖皮质激素治疗。治疗减轻了局部炎症，并使其中一名患者恢复视力。
展开英文摘要原文
We report two patients who displayed evidence of localized ocular inflammation after CAR T-cell infusion. To manage the resulting severe visual impairment, systemic corticosteroids were administered to both patients. This treatment led to a reduction in local inflammation and restored vision in one of the patients.
论文信息
- 作者
- Herr PM、Brantl V、Priglinger SG、Foerster P、Thurau S
- 通讯作者单位
- Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany.Germany
- 文献类型
- 病例报告 · 读者来信
- 期刊
- Ocular immunology and inflammation2024 Nov
- 原文标识
- PubMed 38579172 · DOI 10.1080/09273948.2024.2333393