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CAR-T 细胞治疗后继发恶性肿瘤报道后的未解问题

英文原题:Unanswered questions following reports of secondary malignancies after CAR-T cell therapy.

查看英文原题

Unanswered questions following reports of secondary malignancies after CAR-T cell therapy.

PubMed 2024/02/01(内容时间) Nat Med Q1 · IF 52.5(JCR 2025)

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中文摘要

关于CAR-T 细胞治疗后出现T细胞恶性肿瘤的报告值得调查,但现有随访研究数据提示,与其他癌症治疗相比,其风险较低。

展开英文摘要原文

Reports of T cell malignancies after CAR-T cell therapy should be investigated, but existing data from follow-up studies suggest a low risk compared with other cancer treatments.

论文信息

作者
Levine BL、Pasquini MC、Connolly JE、Porter DL、Gustafson MP、Boelens JJ、Horwitz EM、Grupp SA
单位
Center for Cellular Immunotherapies and Department of Pathology and Laboratory Medicine, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA. levinebl@pennmedicine.upenn.edu.United States
期刊
Nature medicine2024 Feb
原文标识
PubMed 38195751 · DOI 10.1038/s41591-023-02767-w