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造血细胞移植和 CAR-T 细胞疗法中的远程医疗

英文原题:Telemedicine in Hematopoietic Cell Transplantation and Chimeric Antigen Receptor-T Cell Therapy.

查看英文原题

Telemedicine in Hematopoietic Cell Transplantation and Chimeric Antigen Receptor-T Cell Therapy.

PubMed 2023/08/15(内容时间) Cancers (Basel) Q2 · IF 4.8(JCR 2025)

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中文摘要

远程医疗在基层医疗、慢性病患者和实体器官恶性肿瘤患者的医疗服务提供中发挥了重要作用。然而,由于体格检查是照护的重要环节,远程医疗在血液系统恶性肿瘤、造血细胞移植(HCT)或CAR-T(CAR-T)细胞治疗等亚专科中的应用并不普遍。COVID-19 大流行期间,为优先保护免疫功能低下患者,我们广泛采用了远程医疗。HCT 和 CAR-T 疗法在高危血液系统恶性肿瘤中的应用持续增加,尤其适用于必须前往专科中心接受治疗的老年和体弱患者。

总体而言,HCT 和 CAR-T 照护高度复杂,需要患者、照护者以及专科教学医院多学科团队共同投入。公共卫生紧急事件(PHE)期间,各医疗系统均针对危机进行了调整并迅速采取措施。远程医疗是服务医疗资源不足地区的重要方式,在 COVID-19 PHE 期间迅速扩展,且不受地理区域限制。PHE 期间实践所产生的数据正在推动远程医疗领域发展,尤其是 HCT 和 CAR-T 等复杂治疗专科。本综述考察远程医疗在 HCT 和细胞治疗照护模式中的现有证据,涵盖患者的急性期及长期照护。

展开英文摘要原文

Telemedicine has played an important role in delivering healthcare for primary care, chronic disease patients, and those with solid organ malignancies.

However, its application in subspecialties such as hematologic malignancies, hematopoietic cell transplantation (HCT), or chimeric antigen receptor-T cell (CAR-T) therapy is not widespread since physical examination is a vital component in delivering care. During the COVID-19 pandemic, we widely used telemedicine, since protecting our immunocompromised patients became our top priority. The employment of HCT and CAR-T therapies continues to grow for high-risk hematologic malignancies, particularly in older and frail patients who must visit specialty centers for treatment access. Generally, HCT and CAR-T therapy care is highly complex, necessitating commitment from patients, caregivers, and a multidisciplinary team at specialty academic centers.

All healthcare systems adapted to the crisis and implemented rapid changes during the COVID-19 public health emergency (PHE). Telemedicine, a vital modality for delivering healthcare in underserved areas, experienced rapid expansion, regardless of the geographic region, during the COVID-19 PHE.

The data emerging from practices implemented during the PHE are propelling the field of telemedicine forward, particularly for specialties with complex medical treatments such as HCT and CAR-T therapy. In this review, we examine the current data on telemedicine in HCT and cellular therapy care models for the acute and long-term care of our patients.

论文信息

作者
Gandhi AP、Lee CJ
第一作者单位
Center for Hematologic Malignancies, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA.United States
通讯作者单位
Fred Hutch Cancer Research Center, Clinical Research Division, Seattle, WA 98109, USA.United States
文献类型
综述
期刊
Cancers2023 Aug 15
原文标识
PubMed 37627136 · DOI 10.3390/cancers15164108