CAR-T 细胞治疗在神经系统疾病中应用的最新概述

Genetically modified immune cells, especially CAR-T cells, have captured the attention of scientists over the past 10 years. In the fight against cancer, these cells have a special place. Treatment for hematological cancers, autoimmune disorders, and cancers must include CAR-T cell therapy. Determining the therapeutic targets, side effects, and use of CAR-T cells in neurological disorders, including cancer and neurodegenerative diseases, is the goal of this study.

Due to advancements in genetic engineering, CAR-T cells have become crucial in treating some neurological disorders. CAR-T cells have demonstrated a positive role in treating neurological cancers like Glioblastoma and Neuroblastoma due to their ability to cross the blood-brain barrier and use diverse targets.

However, CAR-T cell therapy for MS diseases is being researched and could be a potential treatment option.

This study aimed to access the most recent studies and scientific articles in the field of CAR-T cells in neurological diseases and/or disorders.