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免疫治疗:癌症治愈的新靶点(综述)

英文原题:Immunotherapy: A new target for cancer cure (Review).

查看英文原题

Immunotherapy: A new target for cancer cure (Review).

PubMed 2023/03/31(内容时间) Oncol Rep Q2 · IF 4.7(JCR 2025)

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中文摘要

癌症是全球死亡的主要原因,全球范围内癌症呈流行态势。免疫治疗已成为一种有前景的抗癌疗法。特别是溶瘤病毒通过病毒自我复制和抗肿瘤免疫反应破坏癌细胞而不破坏正常组织,显示出癌症治疗的潜力。本综述讨论了免疫系统在肿瘤治疗中的作用。从主动免疫和被动免疫治疗方面简要介绍了治疗肿瘤的策略,并重点介绍了树突状细胞疫苗和溶瘤病毒,以及血型A抗原在实体瘤治疗中的应用。

展开英文摘要原文

Cancer is the leading cause of death globally and there is a worldwide cancer epidemic. Immunotherapy has emerged as a promising anticancer therapy. In particular, oncolytic viruses destroy cancer cells without destroying normal tissue via viral self‑replication and anti‑tumor immune responses, showing potential for cancer therapy.

The present review discusses the role of the immune system in the treatment of tumor. The strategies for treating tumors are briefly introduced from aspects of active immunization and passive immunotherapy and the dendritic cell vaccines and oncolytic viruses are highlighted, as well as use of blood group A antigen in the treatment of solid tumors.

论文信息

作者
Zhao F、Shen D、Shang M、Yu H、Zuo X、Chen L、Huang Z、Li L
单位
Medical Laboratory Center, Chifeng Municipal Hospital/Chifeng Clinical College, Inner Mongolia Medical University, Chifeng 024000, P.R. China.Mongolia
文献类型
综述
期刊
Oncology reports2023 May
原文标识
PubMed 36999633 · DOI 10.3892/or.2023.8537