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复发性胶质母细胞瘤患者的非随机对照试验:自体肿瘤裂解物负载树突状细胞疫苗的前景

英文原题:Nonrandomised controlled trial in recurrent glioblastoma patients: the promise of autologous tumour lysate-loaded dendritic cell vaccination.

查看英文原题

Nonrandomised controlled trial in recurrent glioblastoma patients: the promise of autologous tumour lysate-loaded dendritic cell vaccination.

PubMed 2023/02/15(内容时间) Br J Cancer Q1 · IF 7.8(JCR 2025)

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中文摘要

最近,Liau等人报告了在胶质母细胞瘤患者中测试DCVax-L疫苗的3期临床试验结果。尽管取得了有希望且显著的结果,但该研究的设计和漫长的招募期值得一些反思。

展开英文摘要原文

Recently, Liau et al. reported the results of Phase 3 clinical trial testing DCVax-L vaccines on patients with glioblastoma. Despite the promising and significant results obtained, the study design and the long-lasting period of recruitment of this work deserve some reflection.

论文信息

作者
Pasqualetti F、Zanotti S
第一作者单位
Department of Oncology, University of Oxford, OX3 7DQ, Oxford, UK. francesco.pasqualetti@oncology.ox.ac.uk.United Kingdom
通讯作者单位
Anatomic Pathology Unit, IRCCS Humanitas University Research Hospital, Milan, Italy. s.zanotti@aol.com.Italy
文献类型
对照临床试验
期刊
British journal of cancer2023 Oct
原文标识
PubMed 36792723 · DOI 10.1038/s41416-023-02194-1