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与微小根毛霉呼吸道感染相关的内生真菌根毛霉共生菌根瘤菌属菌血症

英文原题:Endofungal Mycetohabitans rhizoxinica Bacteremia Associated with Rhizopus microsporus Respiratory Tract Infection.

查看英文原题

Endofungal Mycetohabitans rhizoxinica Bacteremia Associated with Rhizopus microsporus Respiratory Tract Infection.

PubMed 2022/10/01(内容时间) Emerg Infect Dis Q1 · IF 7.9(JCR 2025)

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中文摘要

我们报告了美国加利福尼亚州一名65岁女性在接受CAR-T 细胞治疗多发性骨髓瘤期间发生Mycetohabitans rhizoxinica菌血症。患者出现急性脑梗死和肺炎;从气管吸出物中分离出小孢根霉。全基因组测序证实血液中的细菌与霉菌内的内生真菌细菌在遗传上完全相同。

展开英文摘要原文

We report Mycetohabitans rhizoxinica bacteremia in a 65-year-old woman in California, USA, who was undergoing chimeric antigen receptor T-cell therapy for multiple myeloma. Acute brain infarction and pneumonia developed; Rhizopus microsporus mold was isolated from tracheal suction. Whole-genome sequencing confirmed bacteria in blood as genetically identical to endofungal bacteria inside the mold.

论文信息

作者
Yang S、Anikst V、Adamson PC
文献类型
病例报告 · 美国 NIH 资助研究
期刊
Emerging infectious diseases2022 Oct
原文标识
PubMed 36148964 · DOI 10.3201/eid2810.220507