CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题：Current State of Cell Therapies for Genitourinary Malignancies.
Current State of Cell Therapies for Genitourinary Malignancies.
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
泌尿生殖系统（GU）肿瘤从免疫检查点抑制剂等免疫治疗中获益良多。然而，这些药物的持久临床缓解率仍然相对较低，需要更多创新的免疫治疗策略。过继性细胞疗法近年来在肿瘤治疗中取得了显著进展，在GU肿瘤治疗中具有巨大潜力。本综述总结了细胞治疗策略在肾细胞癌、膀胱癌以及前列腺癌和阴茎癌治疗中的当前进展。此外，还回顾了过继性细胞疗法在GU肿瘤中当前和过去的临床试验。最后，讨论了细胞疗法在GU肿瘤中的未来前景。
Genitourinary (GU) cancers have greatly benefited from immunotherapy treatments, such as immune checkpoint inhibitors.
However, the durable clinical response rate for these agents remains relatively low, calling for more innovative immunotherapy approaches. Adoptive cell therapy has shown a significant advancement in the treatment of cancer in recent years and represents a great potential for the treatment of GU cancers. This review summarizes the current advancements in cellular therapy strategies for the treatment of renal cell carcinoma, bladder cancer, and prostate and penile cancers.
Further, current and past clinical trials of adoptive cell therapy in GU tumors are reviewed.
Finally, a perspective on the future of cell therapy in GU tumors is discussed.
MEMBER ACCOUNT
登录成功会直接打开下一页。
