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新前沿:CAR-T 细胞治疗在多发性骨髓瘤中的作用

英文原题:New Frontiers: The Role of CAR T-Cell Therapy in Multiple Myeloma.

查看英文原题

New Frontiers: The Role of CAR T-Cell Therapy in Multiple Myeloma.

PubMed 2022/05/23(内容时间) J Adv Pract Oncol

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中文摘要

多发性骨髓瘤仍是第二常见的血液系统恶性肿瘤,复发率高,而且每次复发时难治性疾病都很常见。在JADPRO Live Virtual 2021会议上,报告者比较了多发性骨髓瘤CAR-T 细胞治疗的关键性试验,讨论如何识别和管理CAR-T 细胞输注后的常见毒性,并回顾CAR-T 治疗前咨询和治疗后管理。

展开英文摘要原文

Multiple myeloma remains the second most common hematologic malignancy, and relapse rates are high, with refractory disease common with each relapse. Chimeric antigen receptor (CAR)-modified T cells are a promising new treatment, and at JADPRO Live Virtual 2021, presenters compared pivotal trials in CAR T-cell therapy for multiple myeloma, discussed how to recognize and manage common toxicities after CAR T-cell infusion, and reviewed pre-CAR-T consultation and post-CAR-T management.

论文信息

作者
McClanahan A、Spychalla M
单位
Mayo Clinic, Rochester, Minnesota.United States
期刊
Journal of the advanced practitioner in oncology2022 Apr
原文标识
PubMed 35663181 · DOI 10.6004/jadpro.2022.13.3.30