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长期癌症缓解期间 CAR-T 细胞持续存在

英文原题:CAR T cells remain during long-term cancer remission.

查看英文原题

CAR T cells remain during long-term cancer remission.

PubMed 2022/03/11(内容时间) Commun Med (Lond) Q1 · IF 7.4(JCR 2025)

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中文摘要

多种基于嵌合抗原受体(CAR)T细胞的疗法现已获得FDA批准用于治疗癌症。发表在《自然》杂志上的一项研究发现,两名在接受CAR-T 细胞疗法作为临床试验一部分后十多年仍无癌症的患者体内仍存在CAR-T 细胞。

展开英文摘要原文

A number of chimeric antigen receptor (CAR) T cell-based therapies are now approved by the FDA for the treatment of cancer. A study published in Nature found that CAR T cells are still present in two patients who remain cancer-free over a decade after they received CAR T cell therapy as part of a clinical trial.

论文信息

作者
Barnes K
单位
Communications Medicine, https://www.nature.com/commsmed.
期刊
Communications medicine2022
原文标识
PubMed 35603282 · DOI 10.1038/s43856-022-00092-w