CAR-T（CAR-T）细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CAR-T（CAR-T）细胞在血液系统恶性肿瘤中的应用推动了这种免疫治疗形式的显著进展。
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
与细胞治疗相关的心脏疾病及急性白血病新型药物
英文原题：Cardiac Disorders Associated with Cellular Therapy and Novel Agents for Acute Leukemia.
查看英文原题
Cardiac Disorders Associated with Cellular Therapy and Novel Agents for Acute Leukemia.
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中文摘要
过去十年中，多种新型策略成为化疗难治性淋巴增殖性疾病和急性白血病的潜在治疗方法。这些令人振奋的新药显著改变了治疗格局，但相关器官毒性可能较大。本文重点介绍CAR-T 细胞疗法及急性白血病新型治疗方案相关的心脏疾病。
展开英文摘要原文
Several novel strategies have emerged in the last decade as potential therapies for patients with chemorefractory lymphoproliferative diseases and acute leukemia. While these treatments include exciting drugs that dramatically change the landscape of treatment, the organ-toxicity profile associated with these therapies may be significant. This article focuses on cardiac disorders associated with chimeric antigen receptor T-cell (CAR-T) therapy, as well as with novel regimens for acute leukemia.
论文信息
- 作者
- Moshe Y、Ram R
- 单位
- Bone Marrow Transplantation Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.Israel
- 文献类型
- 综述
- 期刊
- The Israel Medical Association journal : IMAJ2022 Mar
- 原文标识
- PubMed 35347930