CAR-T（CAR-T）细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
2020 年 BMT CTN 骨髓瘤协作组研讨会：多发性骨髓瘤的免疫分型与微小残留病检测
英文原题：The 2020 BMT CTN Myeloma Intergroup Workshop on Immune Profiling and Minimal Residual Disease Testing in Multiple Myeloma.
查看英文原题
The 2020 BMT CTN Myeloma Intergroup Workshop on Immune Profiling and Minimal Residual Disease Testing in Multiple Myeloma.
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中文摘要
第五届血液与骨髓移植临床试验网络骨髓瘤协作组“多发性骨髓瘤免疫图谱和微小残留病检测”研讨会，于 2020 年 12 月 3 日星期四作为美国血液学会年会科学研讨会之一举行。研讨会聚焦四个主题：（1）将微小残留病检测纳入临床试验设计和实践；（2）骨髓瘤疾病演化与进展的分子和免疫生物学；（3）新一代测序、新一代流式细胞术及飞行时间质谱流式技术的应用；（4）CAR-T 细胞及其他骨髓瘤细胞疗法。本文总结研讨会报告内容，并讨论该领域未来发展方向。
展开英文摘要原文
The fifth annual Blood and Marrow Transplant Clinical Trials Network Myeloma Intergroup Workshop on Immune Profiling and Minimal Residual Disease Testing in Multiple Myeloma was conducted as one of the American Society of Hematology Annual Meeting Scientific Workshops on Thursday December 3, 2020.
This workshop focused on four main topics: (1) integrating minimal residual disease into clinical trial design and practice; (2) the molecular and immunobiology of disease evolution and progression in myeloma; (3) adaptation of next-generation sequencing, next-generation flow cytometry, and cytometry by time of flight techniques; and (4) chimeric antigen receptor T-cell and other cellular therapies for myeloma. In this report, we provide a summary of the workshop presentations and discuss future directions in the field.
论文信息
- 作者
- Holstein SA、Bahlis N、Bergsagel PL、Bhutani M、Bolli N、Brownstein C、Demolis P、Foureau D
- 单位
- University of Nebraska Medical Center, Omaha, Nebraska. Electronic address: sarah.holstein@unmc.edu.
- 文献类型
- 美国 NIH 资助研究 · 综述
- 期刊
- Transplantation and cellular therapy2021 Oct
- 原文标识
- PubMed 34107340 · DOI 10.1016/j.jtct.2021.05.027
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